Jean-François Mangin, PhD

Jean-François Mangin graduated from Ecole Centrale Paris and received his Ph.D in image analysis from Télécom ParisTech. He is the head of a research group in structural neuroimage analysis located in Neurospin, the high-field MRI center of the CEA. His methodological interest is in building computer vision systems dedicated to the complex structures embedded in neuroimaging data. His neuroscience interest is in modeling the variability of the cortical folding patterns and of U-fiber bundles of white matter.In the Human Brain Project, the European Commission Flagship (, he is the coleader of the Stragegic Human Brain Data subproject with Katrin Amunts. In the context of CATI, his ultimate goal is the inference of imaging-biomarkers from large databases using machine learning.

Section Diffusion/faisceaux

J.-F. Mangin, P. Fillard, Y. Cointepas, D. Le Bihan, V. Frouin, C. Poupon C, Toward global tractography, Neuroimage. 80:290-296, 2013

P Guevara, D Duclap, C Poupon, L Marrakchi-Kacem, P Fillard, D Lebihan, M Leboyer, J Houenou, J-F Mangin, Automatic fiber bundle segmentation in massive tractography datasets using a multi-subject bundle atlas, NeuroImage, 61(4):1083-99, 2012

P. Fillard, M. Descoteaux, A. Goh, S. Gouttard, B. Jeurissen B, J. Malcolm, A. Ramirez-Manzanares, M. Reisert, K. Sakaie, F. Tensaouti, T. Yo T, J.-F. Mangin, and C. Poupon. Quantitative evaluation of 10 tractography algorithms on a realistic diffusion MR phantom. Neuroimage, 56(1):220-34, 2011

Morphology of the cerebral cortex ( à la place de Atrophy from fold opening)

J.-F. Mangin J.-F., M. Perrot, G. Operto, A. Cachia, C. Fischer, J. Lefèvre and D. Rivière, Sulcus Identification and Labeling. In: Arthur W. Toga, editor. Brain Mapping: An Encyclopedic Reference, vol. 1, pp. 365-374. Academic Press: Elsevier, 2015

J.-F. Mangin, G. Auzias, O. Coulon, Z. Y. Sun, D. Rivière, J.Régis J., Sulci as Landmarks. In: Arthur W. Toga, editor. Brain Mapping: An Encyclopedic Reference, vol. 2, pp. 45-52. Academic Press: Elsevier, 2015

D Germanaud, J Lefèvre, R Toro, C Fischer, J Dubois, L Hertz-Pannier, J.-F. Mangin, Larger is twistier: Spectral Analysis of Gyrification (SPANGY) applied to adult brain size polymorphism, NeuroImage, 63(3):1257-72, 2012

Z. Y. Sun, S. Klöppel, D. Rivière, M. Perrot, R. Frackowiak, H. Siebner, and J.-F. Mangin, The Effect of Handedness on the Shape of the Central Sulcus, Neuroimage, 60(1):332-9, 2012

P. Reiner, E. Jouvent, E. Duchesnay, R. Cuingnet, J.-F. Mangin, H. Chabriat, Alzheimer’s Disease Neuroimaging Initiative. Sulcal span in Azheimer’s disease, amnestic mild cognitive impairment, and healthy controls. J Alzheimers Dis. 29(3):605-13, 2012

E. Jouvent, J.-F. Mangin, E. Duchesnay, R. Porcher, M. Düring, Y. Mewald, J. P. Guichard, D. Hervé, S. Reyes, N. Zieren, M. Dichgans, and H. Chabriat. Longitudinal changes of cortical morphology in CADASIL. Neurobiol Aging, 33(5):1002.e29-36, 2012.

E. Jouvent, J.-F. Mangin, D. Hervé, M. Düring, M. Dichgans, and H. Chabriat. Cortical folding influences migraine aura symptoms in CADASIL. J Neurol Neurosurg Psychiatry, 83(2):213-6, 2012.

P. Kochunov, W. Rogers, J.-F. Mangin, and J. Lancaster. A Library of Cortical Morphology Analysis Tools to Study Development, Aging and Genetics of Cerebral Cortex. Neuroinformatics, 2011

M. Perrot, D. Rivière, and J.-F. Mangin. Cortical sulci recognition and spatial normalization. Medical Image Analysis, 15(4):529-550, 2011

G. Auzias, O. Colliot, J. Glaunes, M. Perrot, J.-F. Mangin, A. Trouve, and S. Baillet. Diffeomorphic Brain Registration Under Exhaustive Sulcal Constraints. IEEE Trans Med Imaging, 30(6):1214-1227, 2011.

E. Jouvent, S. Reyes S, J.-F. Mangin, P. Roca, M. Perrot, B. Thyreau, D. Hervé, M. Dichgans, and H. Chabriat. Apathy is related to cortex morphology in CADASIL: A sulcal-based morphometry study. Neurology, 76(17):1472-7, 2011

J. Régis, M. Tamura, M. Park, A. McGonigal, D. Rivière, O. Coulon, F. Bartolomei, N. Girard, D. Figarella-Branger, P. Chauvel, and J.-F. Mangin. Subclinical abnormal gyration pattern, a potential anatomic marker of epileptogenic zone in patients with MRI–negative frontal lobe epilepsy. Neurosurgery, 69(1):80-94, 2011

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